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Sexual health

Ready when you are.

Discreet, clinician-guided ED treatment built on two of the most prescribed molecules in medicine. Reviewed online, shipped plainly, no waiting room.

PinwellRx offers discreet online care for sexual health: generic sildenafil and tadalafil - the FDA-approved active ingredients in Viagra® and Cialis® - and a compounded combination when a clinician finds it appropriate. Compounded products are not FDA-approved. Plain packaging, licensed U.S. pharmacies, and a price you see before you pay.

Sources: FDA prescribing information, peer-reviewed clinical trials and NIH literature · Updated August 2026

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Takes about 10 minutes · a clinician can decline · full refund if not prescribed

Existing pages

Sexual health explainer

Existing explainer for clinician-guided options on this site.

How do the visits and medications actually work?

Map of the visit. A clinician can still decline.

Who should not start?

Contraindications and what to do if something goes wrong.

What do the words on your vial and visit notes mean?

Plain-language terms, not a storefront.

Does PinwellRx ship to my state?

Nationwide coverage check. Houston is not a clinic you visit.

1 in 3

Men experience ED at some point

It is one of the most common conditions men bring to a licensed clinician, and one of the most treatable. The medicines are decades old and well understood. FDA approval belongs to a specific finished product made by a specific manufacturer. It does not transfer to a compounded preparation that happens to contain the same active ingredient. What most men actually need is a private way to have the conversation.

Prescription only. A licensed clinician reviews your health history and decides whether treatment is medically appropriate. These medicines are never combined with nitrates.

The medications

This page is general health information, not medical advice. It cannot diagnose you or tell you what treatment is right for you. Only a licensed clinician who has reviewed your history can do that, and they may decide treatment is not appropriate. Individual results vary and no outcome is guaranteed.

Proven molecules.
Seven ways to take them.

Sildenafil for the moment. Tadalafil for the weekend. Combinations and liposomal forms when your clinician decides one fits. Compounded options are not FDA-approved.

Prescription tablet

Tadalafil

Up to 36 hours

The active ingredient in Cialis®. A window of up to 36 hours, or a low daily dose so timing never enters the equation.

Tadalafil can remain effective for up to 36 hours. That is how long it works, not how long it interacts with nitrates. The labeling says at least 48 hours should pass after the last tadalafil dose before nitrate treatment is even considered. If you need emergency care, tell the team that you take tadalafil and exactly when your last dose was.

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Compounded

Sildenafil plus tadalafil dual compound bottle

Sildenafil + Tadalafil

Dual pathway

Both molecules in one compounded tablet, for men whose clinician decides a combined approach fits. Compounded medications are not FDA-approved.

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Compounded

Sildenafil + Tadalafil, Liposomal

Liposomal

Both molecules in a liposomal preparation rather than a tablet. The lipid carrier is intended to aid absorption. Compounded medications are not FDA-approved.

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Compounded

Tadalafil and apomorphine bottle with lavender label

Tadalafil + Apomorphine

Two pathways

Tadalafil works locally on blood flow. Apomorphine acts centrally, on dopamine receptors involved in arousal signalling. Compounded medications are not FDA-approved.

The apomorphine labeling contraindicates taking it with any drug of the 5HT3 antagonist class. That class is the anti-nausea medicines ondansetron, granisetron, dolasetron and palonosetron, plus alosetron, which is used for the bowel. Profound low blood pressure and loss of consciousness have been reported when apomorphine was given with ondansetron. Ondansetron is one of the medicines most often prescribed for the nausea of a GLP-1, so if you take a GLP-1, or you are given anything for nausea by any clinician, say so before a preparation containing apomorphine is prescribed or taken.

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Compounded

Sildenafil and apomorphine bottle with lavender label

Sildenafil + Apomorphine

Fast + central

Sildenafil acts quickly on blood flow; apomorphine acts centrally on arousal pathways. Compounded medications are not FDA-approved.

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Compounded

Four-active liposomal

Clinician-selected

Three PDE5 inhibitors plus apomorphine in one liposomal dose. Your clinician decides whether a multi-active formulation is appropriate. Compounded medications are not FDA-approved.

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Timing

How the two molecules pace themselves.

Sildenafil arrives fast and steps back the same evening. Tadalafil takes the scenic route and stays. Same family, very different clocks.

Sildenafil · works about 4-6 hours

Tadalafil · can work up to 36 hours

Illustrative timing based on the FDA-approved labels for sildenafil and tadalafil. Onset and duration vary by person, dose, and meals. Not a guarantee.

How it works

Private from the first click.

A short online intake

Health history, medications, and what you want to change. About five minutes, from anywhere.

A licensed clinician reviews it

Heart health and current medications matter here, especially nitrates. If treatment is appropriate, they prescribe.

Shipped in plain packaging

Dispensed by a licensed US pharmacy and delivered to your door. Nothing on the box says what is in it.

Adjust as you go

Dose too strong, too weak, or timing wrong for your life? Message your care team and your clinician adjusts.

Prescription medications are available only if a licensed clinician determines treatment is medically appropriate after your evaluation. Do not use PDE5 inhibitors with nitrates. Compounded medications are not FDA-approved; FDA does not review compounded medications for safety, effectiveness, or quality before marketing. Availability varies by state.

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Sources

Trial results and label statements belong to the cited FDA-approved products and publications - they are not claims about compounded medications. Compounded medications are not FDA-approved.

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Currently offering services in all 50 states plus Washington D.C. Some services may not be available in all 50 states or Washington D.C. Subject to change. Compounded medications are not FDA-approved; FDA does not review compounded medications for safety, effectiveness, or quality before marketing. Prescriptions are available only following evaluation by a licensed clinician who determines that treatment is medically appropriate. Medications are dispensed by independent state-licensed pharmacies. PinwellRx does not manufacture or compound medications.

Cancellation and refunds. You may cancel your subscription at any time before your next billing date; cancellation stops future charges and does not refund charges already processed. If a licensed clinician determines that treatment is not appropriate for you, you are refunded in full. Medications that have shipped cannot be returned or refunded, as required by pharmacy law. To cancel or request a refund, see our Cancellation & Refund Policy and Terms of Use, or contact us at contact@pinwellrx.com.

Ready when you are.

Proven molecules.Seven ways to take them.

How the two molecules pace themselves.

Private from the first click.

Proven molecules.
Seven ways to take them.