What is sermorelin?
Sermorelin is a growth-hormone-releasing hormone analog. Prakash and Goa reviewed that pharmacology in BioDrugs (1999): it is a synthetic peptide corresponding to a fragment of GHRH that signals the pituitary.
Related: What is peptide therapy? and What is NAD+? Unlike synthetic growth hormone itself, sermorelin works upstream: it asks the pituitary to do its own work, which keeps the body's feedback loops in the picture. It is typically prescribed as a small nightly subcutaneous injection, because the body's natural growth hormone release is concentrated in early sleep. PinwellRx lists sermorelin, nightly, at $229 per 4 weeks. Whether it is appropriate is a clinical decision. The clinician can say no.
Is sermorelin growth hormone?
No. Sermorelin is not growth hormone. It is a GHRH fragment that asks the pituitary to release its own growth hormone.
That distinction matters for how clinicians think about it, and it is why this page will not sell sermorelin as a steroid or as an anti-aging cure. Compounded sermorelin is not FDA-approved.
Is compounded sermorelin FDA-approved?
No. Compounded sermorelin is not FDA-approved. It is prepared by a licensed 503A pharmacy for a named patient when a licensed clinician determines it is appropriate.
Compounded medications are not FDA-approved. A licensed clinician reviews your history and may decline. If prescribed, a licensed U.S. 503A pharmacy prepares the medication and ships to all 50 states. Houston is HQ. Educational content, not medical advice.